Phase 3 Clinical Trials in 2014

2014 Phase 3 Research Overview

Phase 3 clinical trials started in 2014 provide a snapshot of the medical research landscape. In total, 5 such trials were initiated. 4 trials have been completed. Leading sponsors include National Cancer Institute (NCI), AstraZeneca, Pfizer.

Phase 3 Trials

Trial Status

COMPLETED: 4 trials
ACTIVE NOT RECRUITING: 1 trial

Top Sponsors (2014)

National Cancer Institute (NCI) (1 trial)
AstraZeneca (1 trial)
Pfizer (1 trial)
Hoffmann-La Roche (1 trial)
Eli Lilly and Company (1 trial)

Phase 3 Trials Started in 2014

Randomized Phase 3 Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (AMG 479, NSC# 750008) to Multiagent Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma

NCT02306161 · ACTIVE NOT RECRUITING · Phase 3 · National Cancer Institute (NCI)

A Phase III, Double-blind, Randomised Study to Assess the Safety and Efficacy of AZD9291 Versus a Standard of Care Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor as First Line Treatment in Patients With Epidermal Growth Factor Receptor Mutation Positive, Locally Advanced or Metastatic Non Small Cell Lung Cancer.

NCT02296125 · COMPLETED · Phase 3 · AstraZeneca

A Multicenter, Randomized, Double-blind, Parallel-group, Phase 3 Study To Demonstrate Non-inferiority For The Efficacy Of A Once Daily Dose Of Tofacitinib Modified Release Tablet To A Twice Daily Dose Of The Immediate Release Tablet In Adult Patients With Rheumatoid Arthritis On Background Methotrexate

NCT02281552 · COMPLETED · Phase 3 · Pfizer

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Efficacy and Safety Study of Gantenerumab in Patients With Mild Alzheimer's Disease; Part II: Open-Label Extension For Participating Patients

NCT02051608 · COMPLETED · Phase 3 · Hoffmann-La Roche

Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4 Study)

NCT02008357 · COMPLETED · Phase 3 · Eli Lilly and Company

Frequently Asked Questions

How many Phase 3 trials started in 2014?

5 Phase 3 clinical trials were started in 2014 according to ClinicalTrials.gov data tracked by ReadTheTrial.

What is Phase 3 in clinical trials?

Phase 3 trials are large-scale pivotal studies with 300-3,000+ participants for FDA approval.

Are any 2014 Phase 3 trials recruiting?

Most trials from 2014 have completed enrollment. Visit the recruiting page for current opportunities.